絲甘蛋白聚糖(SRGN)重組蛋白
Recombinant Serglycin (SRGN)
PRG; PPG; PRG1; proteoglycan 1, secretory granule
- 編號(hào)RPC869Hu01
- 物種Homo sapiens (Human，人)相同的名稱，不同的物種。
- 來(lái)源原核表達(dá)
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測(cè)定)
- 亞細(xì)胞定位分泌, 細(xì)胞質(zhì), 細(xì)胞外基質(zhì)
- 預(yù)測(cè)分子量18.4kDa
- 實(shí)際分子量22kDa(差異分析請(qǐng)參閱說(shuō)明書)
- 片段與標(biāo)簽Tyr28~Leu158 with N-terminal His Tag
- 緩沖液成份20mM Tris, 150mM NaCl緩沖液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性狀凍干粉
- 純度> 95%
- 等電點(diǎn)4.6
- 應(yīng)用Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請(qǐng)參見活性蛋白。 - 下載英文說(shuō)明書 中文說(shuō)明書
- 規(guī)格10μg50μg200μg1mg5mg
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)
Figure . Gene Sequencing (extract)
Figure. SDS-PAGE
通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲(chǔ)存
避免反復(fù)凍融。2-8°C不超過一個(gè)月，-80°C不超過12個(gè)月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。
增值服務(wù)
相關(guān)產(chǎn)品
| 編號(hào) | 適用物種：Homo sapiens (Human，人) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| RPC869Hu01 | 絲甘蛋白聚糖(SRGN)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| CPC869Hu21 | 絲甘蛋白聚糖(SRGN)卵白蛋白偶聯(lián)物 | Immunogen; SDS-PAGE; WB. |
| PAC869Hu01 | 絲甘蛋白聚糖(SRGN)多克隆抗體 | WB |
| PAC869Hu08 | 絲甘蛋白聚糖(SRGN)多克隆抗體 | ICC/IF |
| MAC869Hu22 | 絲甘蛋白聚糖(SRGN)單克隆抗體 | WB,IHC,ICC/IF |
| MAC869Hu21 | 絲甘蛋白聚糖(SRGN)單克隆抗體 | WB; IHC; ICC; IP. |
| SEC869Hu | 絲甘蛋白聚糖(SRGN)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| CEC869Hu | 絲甘蛋白聚糖(SRGN)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMC869Hu | 絲甘蛋白聚糖(SRGN)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
| Irish Journal of?Medical?Science | The role of increased synovial fluid A disintegrin and metalloproteinase with thrombospondin motifs4 and serglycin levels in osteoarthritis[Pubmed: 30536194] |
| MOLECULAR AND CELLULAR BIOCHEMISTRY | SRGN, a new identified shear-stress-responsive gene in endothelial cells[Pubmed: 32712749] |
| Theranostics | Significance of serglycin and its binding partners in autocrine promotion of metastasis in esophageal cancer[33456569] |
| CELLULAR ONCOLOGY | Cancer?\associated fibroblasts secrete hypoxia?\induced serglycin to promote head and neck squamous cell carcinoma tumor cell growth in vitro and in vivo by ?-[33651283] |
| Cell Death Dis | Serglycin induces osteoclastogenesis and promotes tumor growth in giant cell tumor of bone[34556636] |